Annotation Detail
Information
- Associated Genes
- APOA5
- Associated Variants
-
ZPR1 c.*724C>G
(
ENST00000227322.8 )
ZPR1 c.*724C>G ( ENST00000227322.8 ) - Associated Disease
- Coronary heart disease
- Source Database
- DisGeNET
- Description
- MG 18∶2 showed an enrichment (P-value = 0.002) of significant associations with CHD-associated SNPs (P-value = 1.2×10-7 for association with rs964184 in the ZNF259/APOA5 region) and a weak, but positive causal effect (odds ratio = 1.05 per SD increment in MG 18∶2, P-value = 0.05) on CHD, as suggested by Mendelian randomization analysis.
- Pubmed
- 25502724
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0311472588973682
- Year of publication
- 2014
Drugs