Annotation Detail

Information
Associated Genes
TNFRSF1B
Associated Variants
TNFRSF1B p.Met196Arg (p.M196R) ( ENST00000376259.7 )
TNFRSF1B p.Met196Arg (p.M196R) ( ENST00000376259.7 )
Associated Disease
Ovarian Diseases
Source Database
DisGeNET
Description
In conclusion, the M196R (676 T-->G) variant in exon 6 of TNFRSF1B is associated with hyperandrogenism and PCOS, further suggesting a role for inflammatory cytokines in the pathogenesis of these disorders.
Pubmed
12161545
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2002
Drugs