Annotation Detail

Information
Associated Genes
PTCSC3
Associated Variants
rs944289
rs944289
Associated Disease
Thyroid carcinoma
Source Database
DisGeNET
Description
Association of rs944289, which was previously known to confer risk for thyroid cancer, with FA, and the correlation between PTCSC3 and NRG1 expression demonstrates that predisposing genetic factors are partly common for benign and malignant thyroid tumors, and imply broader roles of the pathways they underlie in thyroid tumorigenesis, not limited to carcinogenesis.
Pubmed
25562676
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs