Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
The ATP-binding cassette transporter A1 (ABCA1) R230C variant is associated with low HDL cholesterol levels, obesity, and the metabolic syndrome in Mexican-Mestizos.
Pubmed
18003760
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.125819831445525
Year of publication
2008
Drugs