Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
ABCA1 p.Arg230Cys (p.R230C) ( ENST00000374736.8, ENST00000423487.6, ENST00000678995.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
The R230C variant of the ATP binding cassette protein A1 (ABCA1) gene is associated with a decreased response to glyburide therapy in patients with type 2 diabetes mellitus.
Pubmed
23273975
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0247224115342875
Year of publication
2013
Drugs