Annotation Detail

Information
Associated Genes
HLA-DRB4
Associated Variants
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000428835.6, ENST00000418931.7 )
HLA-DPB1 c.*550A>G ( ENST00000416804.2, ENST00000418931.7, ENST00000428835.6 )
Associated Disease
hepatitis B
Source Database
DisGeNET
Description
A phylogenetic analysis revealed that the isolated HBV was genotype H. In this patient, the elevated peak level of HBV-DNA and the risk alleles at human genome single nucleotide polymorphisms s3077 and rs9277535 in the human leukocyte antigen-DP locus were considered to be risk factors for chronic infection.
Pubmed
24659896
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00407162808120455
Year of publication
2013
Drugs