Annotation Detail

Information
Associated Genes
HLA-DQB1
Associated Variants
HLA-DQB1 p.Phe41Cys (p.F41C) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
HLA-DQB1 p.Phe41Ser (p.F41S) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
HLA-DQB1 p.Phe41Tyr (p.F41Y) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
HLA-DQB1 p.Phe41Cys (p.F41C) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
HLA-DQB1 p.Phe41Ser (p.F41S) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
HLA-DQB1 p.Phe41Tyr (p.F41Y) ( ENST00000374943.8, ENST00000399079.7, ENST00000399082.7, ENST00000399084.5, ENST00000434651.7 )
Associated Disease
Drug-Induced Liver Injury
Source Database
DisGeNET
Description
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.
Pubmed
21570397
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.242367031978602
Year of publication
2011
Drugs