Annotation Detail
Information
- Associated Genes
- IRF4
- Associated Variants
-
IRF4 c.*3466A>G
(
ENST00000380956.9 )
IRF4 c.*3466A>G ( ENST00000380956.9 ) - Associated Disease
- chronic lymphocytic leukemia
- Source Database
- DisGeNET
- Description
- [We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)).]
- Pubmed
- 18758461
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.254278136741733
- Year of publication
- 2008
Drugs