Annotation Detail

Information
Associated Genes
PPARGC1A
Associated Variants
PPARGC1A p.Gly482Ser (p.G482S) ( ENST00000264867.7, ENST00000613098.4 )
PPARGC1A p.Gly482Ser (p.G482S) ( ENST00000264867.7, ENST00000613098.4 )
Associated Disease
Diabetes
Source Database
DisGeNET
Description
The Gly482Ser polymorphism in peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A) has been demonstrated to be associated with diabetes, obesity and hypertension, all of which are important risk factors for left ventricular diastolic dysfunction.
Pubmed
19077249
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Year of publication
2008
Drugs