Annotation Detail

Information
Associated Genes
PPARGC1A
Associated Variants
PPARGC1A p.Gly482Ser (p.G482S) ( ENST00000264867.7, ENST00000613098.4 )
PPARGC1A p.Gly482Ser (p.G482S) ( ENST00000264867.7, ENST00000613098.4 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Genetic studies have suggested that Gly482Ser polymorphism of the PGC-1alpha gene is associated with a higher risk of type 2 diabetes, obesity, and hypertension.
Pubmed
18614852
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0276284460819884
Year of publication
2008
Drugs