Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
NC_000019.10:g.39252525T>G
NC_000019.10:g.39252525T>G - Associated Disease
- Hepatitis C, Chronic
- Source Database
- DisGeNET
- Description
- Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were investigated.
- Pubmed
- 21503910
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0948429671860937
- Year of publication
- 2011
Drugs