Annotation Detail

Information
Associated Genes
PTGS2
Associated Variants
NC_000019.10:g.39252525T>G
NC_000019.10:g.39252525T>G
Associated Disease
Fibrosis, Liver
Source Database
DisGeNET
Description
The present study was designed to assess the contribution of these SNPs to disease progression in patients with chronic hepatitis C. The study enrolled 220 Japanese patients with chronic hepatitis C. Three SNPs, -1195 COX-2, PNPLA3 and IL28B (rs8099917), were genotyped in order to analyze their association with hepatic fibrosis and inflammation.
Pubmed
22863264
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2012
Drugs