Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
NC_000019.10:g.39252525T>G
NC_000019.10:g.39252525T>G
Associated Disease
liver cirrhosis
Source Database
DisGeNET
Description
Multivariable analysis identified four independent factors that were significantly associated with SVR: IL28B SNP rs8099917 genotype (P = 6.90 × 10(-5) ), pre-existence of cirrhosis (P = 3.99 × 10(-3) ), prior treatment response (P = 0.0126), and rapid virological response (P = 0.0239).
Pubmed
24117654
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00833875316436871
Year of publication
2013
Drugs