Annotation Detail
Information
- Associated Genes
- CHRNA3
- Associated Variants
-
CHRNA3 p.Val53= (p.V53=)
(
ENST00000348639.7,
ENST00000326828.6 )
CHRNA3 p.Val53= (p.V53=) ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Identified genome-wide significant loci: 1) corroborated genes implicated in other studies (MTNR1B, ZNF259/APOA5, XPA/FOXE1 (TTF-2), DARC, CCR3, ABO); 2) localized novel genes in plausible biological pathways (PCSK2, ARHGAP11A, CHRNA3); and 3) revealed novel genes with unknown function in obesity pathogenesis (MATK, COL4A1).
- Pubmed
- 23251661
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.120542883744161
- Year of publication
- 2012
Drugs