Annotation Detail

Information
Associated Genes
SLC2A1
Associated Variants
SLC2A1 p.Thr295Met (p.T295M) ( ENST00000426263.10, ENST00000674765.1 )
SLC2A1 p.Arg126Cys (p.R126C) ( ENST00000426263.10, ENST00000674765.1 )
SLC2A1 p.Ser66Phe (p.S66F) ( ENST00000674765.1, ENST00000426263.10 )
SLC2A1 p.Thr295Met (p.T295M) ( ENST00000426263.10, ENST00000674765.1 )
SLC2A1 p.Arg126Cys (p.R126C) ( ENST00000426263.10, ENST00000674765.1 )
SLC2A1 p.Ser66Phe (p.S66F) ( ENST00000426263.10, ENST00000674765.1 )
Associated Disease
GLUT1 deficiency syndrome
Source Database
DisGeNET
Description
In this study, the protein products of the Glut1DS-associated GLUT1 missense mutations, S66F, R126C, and T295M, were characterized using the Glut1-green fluorescent protein (GFP) fusion expressed in CHO cells.
Pubmed
17052934
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.487328930546168
Year of publication
2007
Drugs