Annotation Detail

Information
Associated Genes
TARDBP
Associated Variants
TARDBP p.Gln343Arg (p.Q343R) ( ENST00000700088.1, ENST00000621790.4, ENST00000240185.8, ENST00000629725.2, ENST00000649624.1, ENST00000315091.7, ENST00000616545.4, ENST00000639083.1 )
TARDBP p.Gln343Arg (p.Q343R) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
Associated Disease
AMYOTROPHIC LATERAL SCLEROSIS 10 (disorder)
Source Database
DisGeNET
Description
TDP-43 mutation in familial amyotrophic lateral sclerosis.
Pubmed
18438952
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.24
Year of publication
2008
Drugs