Annotation Detail

Information
Associated Genes
TARDBP
Associated Variants
TARDBP p.Met337Val (p.M337V) ( ENST00000621790.4, ENST00000700088.1, ENST00000240185.8, ENST00000629725.2, ENST00000649624.1, ENST00000616545.4, ENST00000639083.1, ENST00000315091.7 )
TARDBP p.Met337Val (p.M337V) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
Associated Disease
amyotrophic lateral sclerosis
Source Database
DisGeNET
Description
Overexpression of ALS-associated p.M337V human TDP-43 in mice worsens disease features compared to wild-type human TDP-43 mice.
Pubmed
23475610
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.379801509465824
Year of publication
2013
Drugs