Annotation Detail

Information
Associated Genes
TARDBP
Associated Variants
TARDBP p.Gln331Lys (p.Q331K) ( ENST00000649624.1, ENST00000629725.2, ENST00000616545.4, ENST00000639083.1, ENST00000315091.7, ENST00000700088.1, ENST00000621790.4, ENST00000240185.8 )
TARDBP p.Gln331Lys (p.Q331K) ( ENST00000700088.1, ENST00000240185.8, ENST00000315091.7, ENST00000616545.4, ENST00000621790.4, ENST00000629725.2, ENST00000639083.1, ENST00000649624.1 )
Associated Disease
AMYOTROPHIC LATERAL SCLEROSIS 10 (disorder)
Source Database
DisGeNET
Description
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Pubmed
18309045
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.24
Year of publication
2008
Drugs