Annotation Detail

Information
Associated Genes
INS
Associated Variants
INS p.Cys96Ser (p.C96S), INS-IGF2 c.187+887G>C ( ENST00000397262.5, ENST00000381330.5, ENST00000397270.1, ENST00000250971.7, ENST00000512523.1 )
INS p.Cys96Tyr (p.C96Y), INS-IGF2 c.187+887G>A ( ENST00000512523.1, ENST00000397262.5, ENST00000397270.1, ENST00000381330.5, ENST00000250971.7 )
INS p.Cys96Ser (p.C96S), INS-IGF2 c.187+887G>C ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 )
INS p.Cys96Tyr (p.C96Y), INS-IGF2 c.187+887G>A ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 )
Associated Disease
DIABETES MELLITUS, PERMANENT NEONATAL
Source Database
DisGeNET
Description
Permanent neonatal diabetes mellitus due to a C96Y heterozygous mutation in the insulin gene. A case report.
Pubmed
18981553
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.568414698034489
Year of publication
2008
Drugs