Annotation Detail

Information
Associated Genes
ABCC8
Associated Variants
ABCC8 p.Phe132Val (p.F132V) ( ENST00000642271.1, ENST00000683136.1, ENST00000647015.1, ENST00000643260.1, ENST00000389817.8, ENST00000684571.1, ENST00000302539.9, ENST00000646902.1, ENST00000644772.1 )
ABCC8 p.Phe132Leu (p.F132L) ( ENST00000646902.1, ENST00000644772.1, ENST00000302539.9, ENST00000389817.8, ENST00000684571.1, ENST00000643260.1, ENST00000647015.1, ENST00000683136.1, ENST00000642271.1 )
ABCC8 p.Phe132Val (p.F132V) ( ENST00000302539.9, ENST00000389817.8, ENST00000642271.1, ENST00000643260.1, ENST00000644772.1, ENST00000646902.1, ENST00000647015.1, ENST00000683136.1, ENST00000684571.1 )
ABCC8 p.Phe132Leu (p.F132L) ( ENST00000302539.9, ENST00000389817.8, ENST00000642271.1, ENST00000643260.1, ENST00000644772.1, ENST00000646902.1, ENST00000647015.1, ENST00000683136.1, ENST00000684571.1 )
Associated Disease
Developmental Delay, Epilepsy, and Neonatal Diabetes
Source Database
DisGeNET
Description
We identified a novel heterozygous mutation, F132L, in the ABCC8 gene of a patient with severe developmental delay, epilepsy and neonatal diabetes (DEND syndrome).
Pubmed
16613899
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2006
Drugs