Annotation Detail

Information
Associated Genes
KCNJ11
Associated Variants
KCNJ11 p.Arg50Pro (p.R50P) ( ENST00000682350.1, ENST00000682764.1, ENST00000339994.5, ENST00000528731.1 )
KCNJ11 p.Arg50Gln (p.R50Q) ( ENST00000339994.5, ENST00000682350.1, ENST00000682764.1, ENST00000528731.1 )
KCNJ11 p.Arg50Pro (p.R50P) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
KCNJ11 p.Arg50Gln (p.R50Q) ( ENST00000339994.5, ENST00000528731.1, ENST00000682350.1, ENST00000682764.1 )
Associated Disease
Developmental Delay, Epilepsy, and Neonatal Diabetes
Source Database
DisGeNET
Description
In this study, we present a case of developmental delay, epilepsy and neonatal diabetes (DEND) syndrome in a young male patient with the R50P mutation located in the Kir6.2 subunit of the ATP-sensitive K(+) (KATP) channel.
Pubmed
25739471
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00244297684872273
Year of publication
2016
Drugs