Annotation Detail

Information
Associated Genes
ATP1A3
Associated Variants
ATP1A3 p.Ile771Ser (p.I771S), ENSG00000285505 p.Ile758Ser (p.I758S) ( ENST00000543770.5, ENST00000545399.6, ENST00000602133.5, ENST00000648268.1 )
ATP1A3 p.Ile771Ser (p.I771S), ENSG00000285505 p.Ile758Ser (p.I758S) ( ENST00000543770.5, ENST00000545399.6, ENST00000602133.5, ENST00000648268.1 )
Associated Disease
dystonia 12
Source Database
DisGeNET
Description
Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings.
Pubmed
24803225
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.487328930546168
Year of publication
2014
Drugs