Annotation Detail

Information
Associated Genes
OPA1
Associated Variants
OPA1 p.Arg482His (p.R482H) ( ENST00000361510.8, ENST00000361908.8, ENST00000361828.7, ENST00000361150.6, ENST00000361715.6, ENST00000392436.7, ENST00000392437.6, ENST00000643329.1, ENST00000645553.1, ENST00000646793.1 )
OPA1 p.Arg482His (p.R482H) ( ENST00000361150.6, ENST00000361510.8, ENST00000361715.6, ENST00000361828.7, ENST00000361908.8, ENST00000392436.7, ENST00000392437.6, ENST00000643329.1, ENST00000645553.1, ENST00000646793.1 )
Associated Disease
Optic Atrophy, Autosomal Dominant
Source Database
DisGeNET
Description
The association of autosomal dominant optic atrophy and moderate deafness may be due to the R445H mutation in the OPA1 gene.
Pubmed
14644237
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.525531067355009
Year of publication
2003
Drugs