Annotation Detail

Information
Associated Genes
FEV
Associated Variants
HYKK c.337+256T>C ( ENST00000569878.5, ENST00000566332.5, ENST00000388988.9 )
HYKK c.337+256T>C ( ENST00000388988.9, ENST00000566332.5, ENST00000569878.5 )
Associated Disease
Bronchial Hyperreactivity
Source Database
DisGeNET
Description
The rs8034191 SNP genotyped in 551 children from the environment and childhood asthma (ECA) birth cohort study in Oslo, Norway, and in 516 families from six European centers [the Genetics of Asthma International Network (GAIN) study] was tested for genotypic or allelic associations to current or history of asthma, allergic sensitization (≥ one positive skin prick tests), bronchial hyperresponsiveness (BHR), and lung function (FEV(1%) of predicted and FEV(1) /FVC ratio over/ below the 5th percentile).
Pubmed
22017462
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2012
Drugs