Annotation Detail

Information
Associated Genes
TFR2
Associated Variants
TFR2 p.Arg105Ter (p.R105*) ( ENST00000223051.8, ENST00000431692.5, ENST00000462107.1 )
TFR2 p.Arg105Ter (p.R105*) ( ENST00000223051.8, ENST00000431692.5, ENST00000462107.1 )
Associated Disease
Hereditary hemochromatosis
Source Database
DisGeNET
Description
Early onset hereditary hemochromatosis resulting from a novel TFR2 gene nonsense mutation (R105X) in two siblings of north French descent.
Pubmed
15147384
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.125428837441606
Year of publication
2004
Drugs