Annotation Detail

Information
Associated Genes
DHCR7
Associated Variants
DHCR7 p.Thr93Met (p.T93M) ( ENST00000682880.1, ENST00000526780.6, ENST00000683287.1, ENST00000355527.8, ENST00000527316.6, ENST00000407721.6, ENST00000685320.1, ENST00000683714.1, ENST00000682708.1 )
DHCR7 p.Thr93Met (p.T93M) ( ENST00000355527.8, ENST00000407721.6, ENST00000526780.6, ENST00000527316.6, ENST00000682708.1, ENST00000682880.1, ENST00000683287.1, ENST00000683714.1, ENST00000685320.1 )
Associated Disease
Smith-Lemli-Opitz syndrome
Source Database
DisGeNET
Description
Founder effect for the T93M DHCR7 mutation in Smith-Lemli-Opitz syndrome.
Pubmed
14981719
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.610363549988277
Year of publication
2004
Drugs