Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 )
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 )
Associated Disease
Carcinogenesis
Source Database
DisGeNET
Description
The interaction we observed for rs798766 (TMEM129-TACC3-FGFR3) with specific exposure to straight metalworking fluids illustrates the value of integrating germline genetic variation, environmental exposures, and tumor marker data to provide insight into the mechanisms of bladder carcinogenesis.
Pubmed
26374428
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00732893054616819
Year of publication
2015
Drugs