Annotation Detail
Information
- Associated Genes
- TACC3
- Associated Variants
-
TACC3 c.1591+1211T>C
(
ENST00000313288.9,
ENST00000651472.1,
ENST00000652770.1 )
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 ) - Associated Disease
- Carcinoma of bladder
- Source Database
- DisGeNET
- Description
- When we examined detailed data on a prevalent occupational exposure associated with increased bladder cancer risk, straight metalworking fluids, we also observed statistically significant additive interaction for rs798766 (TMEM129-TACC3-FGFR3, P interaction = .02), with the interaction more apparent in patients with tumors positive for FGFR3 expression.All statistical tests were two-sided.
- Pubmed
- 26374428
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2015
Drugs