Annotation Detail
Information
- Associated Genes
- TACC3
- Associated Variants
-
TACC3 c.1591+1211T>C
(
ENST00000313288.9,
ENST00000651472.1,
ENST00000652770.1 )
TACC3 c.1591+1211T>C ( ENST00000313288.9, ENST00000651472.1, ENST00000652770.1 ) - Associated Disease
- Malignant neoplasm of urinary bladder
- Source Database
- DisGeNET
- Description
- The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio = 1.24, P = 9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70 kb from FGFR3, which often harbors activating somatic mutations in low-grade, noninvasive UBC.
- Pubmed
- 20348956
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.123181357594843
- Year of publication
- 2010
Drugs