Annotation Detail

Information
Associated Genes
INS
Associated Variants
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
Associated Disease
diabetes mellitus
Source Database
DisGeNET
Description
Furthermore, the diabetes-associated C-allele of TSPAN8 rs7961581 associated with decreased levels of CIR (4.5% [0.5-8.4]; P = 0.03), of AUC-insulin/AUC-glucose ratio (3.9% [1.2-6.7]; P = 0.005), and of the insulinogenic index (5.2% [1.9-8.6]; P = 0.002).
Pubmed
18567820
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.295274146663208
Year of publication
2008
Drugs