Annotation Detail
Information
- Associated Genes
- TSPAN8
- Associated Variants
-
TSPAN8 c.-110+8029G>A
(
ENST00000393330.6 )
FTO c.46-27777C>A ( ENST00000637001.1, ENST00000637969.1, ENST00000471389.6, ENST00000636218.1, ENST00000636491.1 )
TSPAN8 c.-110+8029G>A ( ENST00000393330.6 )
FTO c.46-27777C>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Of type 2 diabetes-associated genes, the CC/CT genotypes of rs7961581 (TSPAN8) and the obesity-linked AA/AC genotypes of rs8050136 (FTO) were associated with LADA in general, but mainly in low anti-GAD LADA patients (P = 0.004 and P = 0.004, respectively).
- Pubmed
- 19833889
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00527694770136467
- Year of publication
- 2010
Drugs