Annotation Detail

Information
Associated Genes
SCN5A
Associated Variants
SCN5A p.Leu1825Pro (p.L1825P) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
SCN5A p.Leu1825Pro (p.L1825P) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
Associated Disease
Torsades de pointes
Source Database
DisGeNET
Description
The cardiac sodium channel (SCN5A) mutation L1825P has been identified in a patient with drug-induced torsade de pointes precipitated by the IKr blocker cisapride.
Pubmed
16301357
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.247534359069792
Year of publication
2005
Drugs