Annotation Detail
Information
- Associated Genes
- IGF2
- Associated Variants
-
INS-IGF2 c.188-2872A>C
(
ENST00000397270.1,
ENST00000481781.3 )
INS-IGF2 c.188-2872A>C ( ENST00000481781.3, ENST00000397270.1 ) - Associated Disease
- Sore to touch
- Source Database
- DisGeNET
- Description
- We found that men who were 1) homozygous for the rare IGF-II C13790G allele and rare allele for the ApaI (G17200A) SNP demonstrated the greatest strength loss immediately after exercise, greatest soreness, and highest postexercise serum CK activity; 2) homozygous wild type for IGF2AS (G11711T, rs7924316) had the greatest strength loss and most muscle soreness; and 3) homozygous wild type for the IGF2AS G11711T SNP showed the greatest strength loss, highest muscle soreness, and greater CK and myoglobin response to exercise.
- Pubmed
- 17289909
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2007
Drugs