Annotation Detail
Information
- Associated Genes
- PLCE1
- Associated Variants
-
PLCE1 c.1206+19430C>T
(
ENST00000371380.8,
ENST00000692396.1 )
PLCE1 c.1206+19430C>T ( ENST00000371380.8, ENST00000692396.1 ) - Associated Disease
- Squamous cell carcinoma of esophagus
- Source Database
- DisGeNET
- Description
- Our study for the first time suggests that GWAS originated PLCE1 variants do not have independent role in susceptibility of ESCC in northern Indian population; however, a novel haplo-tagging SNP rs7922612 may modify survival outcome of ESCC patients.
- Pubmed
- 25139097
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.244885953697445
- Year of publication
- 2014
Drugs