Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Glu768= (p.E768=) ( ENST00000615310.5, ENST00000355710.8, ENST00000713926.1, ENST00000340058.6 )
RET p.Glu768Asp (p.E768D) ( ENST00000340058.6, ENST00000713926.1, ENST00000355710.8, ENST00000615310.5 )
RET p.Glu768Asp (p.E768D) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Glu768= (p.E768=) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Glu768Asp (p.E768D) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Glu768Asp (p.E768D) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
Medullary carcinoma of thyroid
Source Database
DisGeNET
Description
RET mutation analysis confirmed an E768D mutation in exon 13 in 8 family members, 3 affected with medullary thyroid cancer alone while the other 5 were detected to be mutation carriers.
Pubmed
16736292
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.32
Year of publication
2006
Drugs