Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Gln319Ter (p.Q319*) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Gln319Ter (p.Q319*) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
21-hydroxylase deficiency
Source Database
DisGeNET
Description
Earlier we had reported a large prevalence of the Q318X mutation in the CYP21A2 gene with 35.3% in Tunisian patients with a classical form of 21-hydroxylase deficiency, in contrast with 0.5% to 13.8% as described in other populations.
Pubmed
21532487
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.155016001498359
Year of publication
2011
Drugs