Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Cys620Ser (p.C620S) ( ENST00000713926.1, ENST00000340058.6, ENST00000615310.5, ENST00000355710.8 )
RET p.Cys620Arg (p.C620R) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Cys620Gly (p.C620G) ( ENST00000713926.1, ENST00000340058.6, ENST00000615310.5, ENST00000355710.8 )
RET p.Cys620Ser (p.C620S) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys620Arg (p.C620R) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys620Gly (p.C620G) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
familial medullary thyroid carcinoma
Source Database
DisGeNET
Description
Also, we briefly review our data from a large familial medullary thyroid carcinoma genealogy harboring a germline rearranged during transfection Cys620Arg mutation.
Pubmed
22584721
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.521802048300367
Year of publication
2012
Drugs