Annotation Detail
Information
- Associated Genes
- RAN
- Associated Variants
-
RAN c.*244A>C
(
ENST00000392369.6,
ENST00000541679.7,
ENST00000543796.6,
ENST00000541630.5 )
RAN c.*244A>G ( ENST00000541679.7, ENST00000543796.6, ENST00000541630.5, ENST00000392369.6 )
DICER1 c.*2693A>G ( ENST00000526495.6, ENST00000531162.7, ENST00000674628.2, ENST00000343455.8, ENST00000529720.2 )
RAN c.*244A>C ( ENST00000392369.6, ENST00000541630.5, ENST00000541679.7, ENST00000543796.6 )
RAN c.*244A>G ( ENST00000392369.6, ENST00000541630.5, ENST00000541679.7, ENST00000543796.6 )
DICER1 c.*2693A>G ( ENST00000343455.8, ENST00000526495.6, ENST00000529720.2, ENST00000531162.7, ENST00000674628.2 ) - Associated Disease
- Persistent infection
- Source Database
- DisGeNET
- Description
- We observed that DICER1 rs1057035 CT/CC variant genotypes were associated with a significant decreased risk of HCC (adjusted OR = 0.79, 95% CI = 0.64-0.96) compared with wild-type TT and RAN rs3803012 AG/GG variant genotypes increased the risk of HBV persistent infection compared with AA genotype (adjusted OR = 1.35, 95% CI = 1.03-1.77).
- Pubmed
- 23868705
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2013
Drugs