Annotation Detail
Information
- Associated Genes
- IL17F
- Associated Variants
-
IL17F p.His161Arg (p.H161R)
(
ENST00000336123.5,
ENST00000699946.1 )
IL17F p.His161Arg (p.H161R) ( ENST00000336123.5, ENST00000699946.1 ) - Associated Disease
- Pancreatic Neoplasm
- Source Database
- DisGeNET
- Description
- [The variant 161R form of IL-17F is a natural antagonist of the antiangiogenic effects of wild-type 161H IL-17F, and angiogenesis may play an important role in the metastatic spread of pancreatic cancer. In this preliminary study, we hypothesize that the a]
- Pubmed
- 22142827
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.00236703197860203
- Year of publication
- 2012
Drugs