Annotation Detail

Information
Associated Genes
CD226
Associated Variants
CD226 p.Ser307Cys (p.S307C) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
CD226 p.Ser307Gly (p.S307G) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
CD226 p.Ser307Cys (p.S307C) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
CD226 p.Ser307Gly (p.S307G) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
There has been more evidence that a non-synonymous exchange (rs763361/Gly307Ser) in the gene for CD226 is linked to several autoimmune diseases including multiple sclerosis (MS).
Pubmed
22728856
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0107157166646349
Year of publication
2012
Drugs