Annotation Detail

Information
Associated Genes
FASLG
Associated Variants
CD226 p.Ser307Cys (p.S307C) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
CD226 p.Ser307Gly (p.S307G) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
NC_000001.11:g.172658358C>T
CD226 p.Ser307Cys (p.S307C) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
CD226 p.Ser307Gly (p.S307G) ( ENST00000280200.8, ENST00000577287.5, ENST00000581982.5, ENST00000582621.6 )
NC_000001.11:g.172658358C>T
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
Our meta-analysis demonstrates that the CD226 rs763361 and FASL rs763110 polymorphisms are associated with RA, especially in Asians.
Pubmed
25645050
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.123810117730788
Year of publication
2015
Drugs