Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Cys618Ser (p.C618S) ( ENST00000615310.5, ENST00000355710.8, ENST00000713926.1, ENST00000340058.6 )
RET p.Cys618Arg (p.C618R) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys618Gly (p.C618G) ( ENST00000340058.6, ENST00000713926.1, ENST00000355710.8, ENST00000615310.5 )
RET p.Cys618Ser (p.C618S) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys618Arg (p.C618R) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys618Gly (p.C618G) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
multiple endocrine neoplasia type 2A
Source Database
DisGeNET
Description
C618R mutation in exon 10 of the RET proto-oncogene in a kindred with multiple endocrine neoplasia type 2A and Hirschsprung's disease.
Pubmed
8675603
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.613995490717024
Year of publication
1996
Drugs