Annotation Detail
Information
- Associated Genes
- CYP1A2
- Associated Variants
-
CYP1A2 c.-9-154C>A
(
ENST00000343932.5 )
CYP1A2 c.-9-154C>A ( ENST00000343932.5 ) - Associated Disease
- Neural Tube Defects
- Source Database
- DisGeNET
- Description
- [The association identified between maternal CYP1A2*1F fast oxidation status and NTDs should be examined further in the context of the other substrates of CYP1A2. Maternal caffeine and its metabolites may be associated with increased risk for NTD-affected ]
- Pubmed
- 20641098
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.122367031978602
- Year of publication
- 2010
Drugs