Annotation Detail

Information
Associated Genes
CYP1B1
Associated Variants
CYP1B1 p.Val432= (p.V432=) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
CYP1B1 p.Leu432Val (p.L432V) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
Associated Disease
breast carcinoma
Source Database
DisGeNET
Description
CYP1A1 codon 462 Ile/Val or Val/Val variants and the CYP1B1 codon 432 Leu/Val variant were found more in breast cancer patients </=35 years of age at onset than the common homozygote [odds ratio (OR), 1.6 and 1.7, respectively].
Pubmed
14734460
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0168293960689788
Year of publication
2004
Drugs