Annotation Detail
Information
- Associated Genes
- TRAF1
- Associated Variants
-
STAT4 c.274-23582A>C
(
ENST00000392320.7,
ENST00000358470.8,
ENST00000413064.6,
ENST00000432798.2,
ENST00000450994.2,
ENST00000714287.1 )
STAT4 c.274-23582A>C ( ENST00000358470.8, ENST00000392320.7, ENST00000413064.6, ENST00000432798.2, ENST00000450994.2, ENST00000714287.1 ) - Associated Disease
- Autoimmune Diseases
- Source Database
- DisGeNET
- Description
- STAT4 rs7574865T allele disclosed a significant influence on the risk of developing SLE (P=0.0005; OR 1.62, 95% CI 1.22-2.16) and RA (P=0.008; OR 1.36; 95% CI 1.08-1.71), whereas no effect on these autoimmune diseases was observed for the TRAF1/C5 polymorphisms examined.
- Pubmed
- 18432273
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00554838957344497
- Year of publication
- 2008
Drugs