Annotation Detail
Information
- Associated Genes
- CYP1B1
- Associated Variants
-
UGT1A6 p.Thr181Ala (p.T181A), UGT1A9 c.855+20756A>G, UGT1A7 c.855+10753A>G, UGT1A8 c.856-73489A>G, UGT1A10 c.855+56168A>G
(
ENST00000344644.10,
ENST00000373445.1,
ENST00000373450.5,
ENST00000373426.4,
ENST00000305139.11,
ENST00000373424.5,
ENST00000354728.5 )
CYP1B1 p.Val432= (p.V432=) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 )
UGT1A6 p.Thr181Ala (p.T181A), UGT1A9 c.855+20756A>G, UGT1A7 c.855+10753A>G, UGT1A8 c.856-73489A>G, UGT1A10 c.855+56168A>G ( ENST00000344644.10, ENST00000373445.1, ENST00000373450.5, ENST00000373426.4, ENST00000305139.11, ENST00000373424.5, ENST00000354728.5 )
CYP1B1 p.Leu432Val (p.L432V) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
PON1 p.Gln192Arg (p.Q192R) ( ENST00000222381.8 ) - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- We found for the first time significant associations of CYP1B1 V432L (P=0.045), PON1 Q192R (P=0.039) and UGT1A6 T181A (P=0.025) gene polymorphisms with asthma susceptibility.
- Pubmed
- 19575027
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00263847385068233
- Year of publication
- 2009
Drugs