Annotation Detail

Information
Associated Genes
CFTR
Associated Variants
CFTR p.Gly551Asp (p.G551D) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
CFTR p.Gly551Asp (p.G551D) ( ENST00000003084.11, ENST00000648260.1, ENST00000649406.1, ENST00000649781.2, ENST00000699602.1, ENST00000699605.1 )
Associated Disease
cystic fibrosis
Source Database
DisGeNET
Description
This randomized, double-blind, placebo-controlled trial evaluated ivacaftor in patients with cystic fibrosis aged 6-11 years with a G551D-CFTR mutation on at least one allele.
Pubmed
23590265
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.8
Year of publication
2013
Drugs