Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Cys634Ser (p.C634S) ( ENST00000340058.6, ENST00000713926.1, ENST00000355710.8, ENST00000615310.5 )
RET p.Cys634Arg (p.C634R) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys634Gly (p.C634G) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys634Ser (p.C634S) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys634Arg (p.C634R) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Cys634Gly (p.C634G) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
multiple endocrine neoplasia type 2A
Source Database
DisGeNET
Description
We performed genetic screening in 88 members of an extended family with MEN-2A and found 18 members positive for RET mutation (Cys634Gly).
Pubmed
12150334
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.613995490717024
Year of publication
2002
Drugs