Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Leu790Phe (p.L790F) ( ENST00000615310.5, ENST00000355710.8, ENST00000713926.1, ENST00000340058.6 )
RET p.Leu790Phe (p.L790F) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Leu790Phe (p.L790F) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Leu790Phe (p.L790F) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
multiple endocrine neoplasia type 2A
Source Database
DisGeNET
Description
A new hot spot for mutations in the ret protooncogene causing familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2A.
Pubmed
9506724
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.613995490717024
Year of publication
1998
Drugs