Annotation Detail

Information
Associated Genes
GSTM1
Associated Variants
GSTM1 MUTATION
GSTM1 MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.82, 95% CI: 0.68, 0.99) genotypes were associated with decreased risk, and the GSTM1-K173N-CG (AOR = 1.99, 95% CI: 1.21, 3.25) genotype was associated with an increased risk of colorectal cancer.
Pubmed
20937634
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0943864192202561
Year of publication
2010
Drugs